想法 Shapeflow
Generalization of Tetris: A strategic game with a variety of morphing shapes flowing through topological holes (like digestive tract) with increasing variety and speed, and complementaries (like matching Tetris bricks) that interact to break down into smaller ones, and a global goal to sustain their flow from clogging the system.
想法 Movable Frame Tetris
Instead of moving the falling brick, move the entire tetris frame in the rain of tetris parts; make the frame walls semi-permeable sometimes, and emulate life form eating bricks, and medical interventions to alleviate clogging.
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Andrew Steele的新书《不老》（Ageless）
“我们时代最重要的生物医学问题背后的科学指南：为什么我们会变老，以及我们如何能够阻止它。”《不老》带我们进入医学前沿，科学家正在研究人体的各个方面：DNA，线粒体，干细胞，免疫系统，甚至是“衰老的基因”，已经帮助动物享有了十倍的寿命增长，在不远的未来，可能找到阻止我们自己身体衰退的治疗方法。
我认为Shapeflow的想法可能具有强大的解释力和影响力，尤其是如果我们设计游戏的话，我们称之为“ Body” -您（作为摄取物质（例如，游戏玩家））所经过的这种结构是随着时间的流逝而生病或堵塞的人体，而您作为目标的目标要成功地通过代谢途径网络。玩此类游戏的孩子（或也许是AlphaZeros）可能会设计出许多我们不知道的策略……而且，没有欺骗，亲爱的AI –遍历所有必要的部分，可以获得加分，因此，不会突然将游戏化的人体转变为拓扑甜甜圈。
I think, the idea of Shapeflow may have great explanatory power and potential for impact, especially, if we devise a game -- let's call it "Body" -- where this structure that you (as ingested substance (say, game player)) is travelling through, is a human body that is getting sick or clogged over time, and your target, as a substance, is to go successfully through that network of metabolic pathways. Kids (or maybe AlphaZeros) playing such games might devise many strategies that we do not know of... and, no cheating, dear AI -- with going through all the necessary parts, where you get extra points -- so, that you wouldn't suddenly convert the gamified human body into a topological doughnut.
//如果我们设计一款游戏-我们将其称为“身体”-您（作为摄入物质（例如，游戏玩家）正在经历的这种结构）会随着时间的流逝而生病或阻塞，作为目标，您的目标是成功地通过新陈代谢途径网络。 //
哦，喜欢它！在我的MUTANTU书中，读者可笑地探索了人体内部，例如血管和肠子（我的漫画发生的地方！）:)
// if we devise a game -- let's call it "Body" -- where this structure that you (as ingested substance (say, game player)) is travelling through, is a human body that is getting sick or clogged over time, and your target, as a substance, is to go successfully through that network of metabolic pathways. //
oh, love it! in my MUTANTU book, the readers comically explore the inside of the body, like blood vessels and intestines (where the action of my comics happens!) :)
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正如您可能认为这是一门艺术，通过人体作为游戏世界将具有很高的教育水平（我的意思是：“高度”），这可能会使孩子们对在做一些关于人体的事情上充满信心。例如，如果游戏具有特殊的额外工具，例如您在超级马里奥兄弟公司中收集大蘑菇的工具，给予额外的权力来通过某些路径移动，疏通拥挤的动脉，并让祖母再次看到世界而不会视力忽明忽暗，或者得到超级枪支，可以直通或修复某些路径...该游戏可能非常有趣（且具有教育意义！**）。但是，我应该鼓励转到Shapeflow页面，并提供进一步的评论，因为该主题似乎比较笼统。 ;）
As much as you may think this is an art, going through a human body as a game world would be highly (I mean it: highly) educational, that could result in kids gaining confidence in actually doing something about human bodies. For example, if the game had special extra tools, like what you collect a big mushroom in Super Mario Bros, giving extra powers to move through certain pathways, unclogging congested arteries, and letting grandmother see the world again without flickering eyesight, or getting a super gun, that allows to cut through, or fix certain pathways... That game could be so fun (and educational!) to play. But I should encourage moving to Shapeflow page with further comments, as this topic is more general it seems. ;)